Cameron Diaz & Nicole Richie
Nicole Richie and Cameron Diaz share more than family ties — they’re true besties. Nicole once hilariously asked Cameron to re-enact her favorite scenes from My Best Friend’s Wedding, and Cameron happily played along. Their bond shines through both family gatherings and playful moments, showing they’re not just sisters-in-law but soul sisters who genuinely enjoy making each other laugh.
Amy Schumer & Jennifer Lawrence
Their friendship began when Jennifer emailed Amy after seeing Trainwreck, confessing she was “in love” with her. That quirky start led to texting, vacations in the Hamptons, and a deep, genuine bond. Jennifer quickly proved she wasn’t just Hollywood royalty but “the coolest chick,” according to Amy. Together, they’ve redefined what it means to have a ride-or-die bestie in the spotlight.
Jennifer Lopez & Leah Remini
Jennifer and Leah met at the 2004 Man on Fire premiere and instantly clicked. Lopez has described their friendship as “love at first sight,” built on laughter, loyalty, and endless support. Leah has always been J.Lo’s loudest cheerleader, including during her unforgettable performance at President Joe Biden’s inauguration. Their bond is proof that real friendship in Hollywood can last for decades.
Jennifer Aniston, Courteney Cox & Lisa Kudrow
The Friends trio became the gold standard of Hollywood friendship. Bonded through years on the iconic sitcom, Jennifer, Courteney, and Lisa still prioritize dinners, reunions, and time together. Their connection goes far beyond work — it’s rooted in growing up together in the spotlight. Even years later, they remain inseparable, proving that some TV friendships really do translate into lifelong love.
Tina Fey & Amy Poehler
Meeting in improv training back in 1993, Tina and Amy instantly clicked. Over the years, they’ve become more like sisters than friends, supporting each other through careers, parenting, and life’s challenges. From Saturday Night Live to cohosting the Golden Globes, their chemistry and comedic brilliance have always been matched by genuine affection. Their chosen-family bond makes them one of Hollywood’s most enviable pairs.
Michelle Williams & Busy Philipps
Michelle and Busy’s friendship sparked on the Dawson’s Creek set and blossomed into one of Hollywood’s most heartfelt BFF stories. Busy has said it was “love at first sight,” and over the years, the two have shared everything from red carpets to hair dye adventures. Whether making us laugh with candid moments or standing by each other’s sides, their bond is pure loyalty and love.
Adele & Drake
Though newer, Adele and Drake’s friendship has quickly become legendary. Bonded by admiration and playful banter, they’ve openly talked about collaborating and even spent nights bowling and dining out in L.A. Adele once confessed her deep love for Drake, while he jokingly said he’d “do her laundry” just to spend time with her. Their star-studded bond feels refreshingly real and full of fun.
Kerry Washington & Eva Longoria
Kerry and Eva’s friendship is built on support and sisterhood. When Eva was pregnant with her son Santiago, Kerry was there with wisdom and encouragement, which Eva described as “basically my doula.” They’ve shared countless moments of honesty, laughter, and encouragement, proving that their connection runs deep. Their friendship highlights how powerful it is when women in Hollywood uplift one another.
Ben Affleck & Matt Damon
Ben and Matt’s bromance is one of Hollywood’s longest-lasting. Friends since childhood, their love of acting led to writing Good Will Hunting, which won them an Oscar and cemented their careers. Decades later, they’re still collaborating and supporting each other through highs and lows. Matt has said their bond was formed in “the most important years” — and it shows.
Oprah Winfrey & Gayle King
Oprah and Gayle’s friendship began in 1976 when they worked at a Baltimore TV station. One snowy night, Oprah invited Gayle to stay over, sparking a lifelong connection. Over the decades, they’ve shared careers, vacations, and unshakable loyalty. Their iconic bond is so enduring that they’ve become the ultimate definition of BFFs, inspiring fans around the world with their sisterly love.
Serena Williams & Meghan Markle
Serena and Meghan met at a Super Bowl party in 2014 and clicked instantly over casual conversation. Their friendship has since grown into a powerful sisterhood that has carried them through life’s biggest milestones. Serena has always been a rock for Meghan, and vice versa, proving that even global icons need their safe spaces. Their bond is empowering, real, and truly enviable.
Sophie Turner & Maisie Williams
From Game of Thrones to real life, Sophie and Maisie’s friendship has been nothing short of magical. Maisie was Sophie’s maid of honor at her wedding, and both credit the show with giving them a lifelong sisterhood. Maisie has even joked that the entire HBO series was just a setup to bring her and Sophie together — and fans couldn’t agree more.
Reese Witherspoon & Jennifer Aniston
Their friendship began on Friends when Reese guest-starred as Rachel’s sister, and it grew into something much bigger. Years later, the pair reunited to co-create The Morning Show, proving their connection only deepened with time. Reese has described Jen as incredibly kind and supportive from the start, making their decades-long friendship one of Hollywood’s most inspiring partnerships.
Martha Stewart & Snoop Dogg
Perhaps the most unexpected but iconic duo, Martha and Snoop’s bond blossomed after roasting Justin Bieber in 2015. Their chemistry was so undeniable that it led to their VH1 cooking show. Despite their wildly different backgrounds, they’ve found common ground in humor, authenticity, and mutual respect. Snoop says Martha feels like “family,” and fans can’t get enough of this dynamic, hilarious pairing.