3. Oprah Winfrey

Oprah Winfrey, once a struggling news anchor, built a media empire that faltered in the 2000s. After her talk show went off the air, many questioned her future in television. But Oprah bounced back with OWN, her network, and her unparalleled influence only grew. Today, Oprah is regarded as a media mogul and a philanthropist, inspiring millions with her story of reinvention.