10. Christina Applegate; Turning Down Elle Woods
Christina Applegate openly admits that turning down the role of Elle Woods in Legally Blonde was a huge mistake she still regrets. Wanting to escape the “dumb blonde” stereotype from her earlier roles, she passed on the part that skyrocketed Reese Witherspoon’s career. Despite the missed opportunity, Applegate welcomes her unique path and the adoptability she’s shown facing life’s unexpected challenges.